Doxofylline 100 mg/10 ml is an intravenous injection containing the active ingredient doxofylline at a concentration of 10 mg/ml. It is a prescription-only medication classified as a bronchodilator and is primarily used to manage symptoms of respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD).
Key Details
Formulation: A clear liquid solution for intravenous injection, typically supplied in 10 ml vials or ampoules.
Mechanism of Action: Doxofylline works by relaxing the smooth muscles in the airways of the lungs (bronchodilation) and has mild anti-inflammatory effects. This action widens the air passages, improves airflow, and makes breathing easier.
Uses: It is used to treat and prevent symptoms such as wheezing, chest tightness, shortness of breath, and coughing associated with asthma and COPD. It can also be used for acute exacerbations of these conditions in a hospital setting.
Administration: It must be administered intravenously by a healthcare professional. It is not a rescue medication for sudden breathing problems, so a fast-acting inhaler should always be kept available.
Common Side Effects
Most side effects are typically mild and may include:
Nausea and vomiting
Stomach pain/upset stomach
Headache
Restlessness or insomnia (difficulty sleeping)
Tremors (unintentional muscle movements)
Palpitations (feeling the heart beat too hard or fast)
Important Warnings and Precautions
Medical Supervision: The injection should be used only under medical supervision.
Contraindications: It should not be used if you are allergic to doxofylline or other xanthine derivatives. It is also not recommended for patients with acute myocardial infarction (heart attack) or severe hypotension (low blood pressure).
Interactions: Inform your doctor about any pre-existing conditions (liver, kidney, or heart problems) and all other medications you are taking, as interactions can occur.
Lifestyle: Avoid smoking and consuming large amounts of caffeinated products (coffee, tea, dark chocolate), as these can increase side effects.
Pregnancy/Breastfeeding: Consult a doctor if you are pregnant or breastfeeding, as safety information is limited.
